Wednesday, February 19, 2014

Why nutritional or complementary medicine?


About 2,500 years ago, Hippocrates regarded food as a primary form of medicine, his famous dictum was “Let your food be your medicine and let your medicine be your food”. Diet has also been an integral element of Ayurvedic and traditional Chinese medicine since their inception thousands of years ago. Unfortunately, today the importance of diet and overall nutrition is often overlooked by conventional medicine. Further very few physicians receive any education about nutrition during their medical training. Dr. Carolyn Dean, a nutritional medicine doctor from the United States says that “doctors generally do not learn about nutrition or nutrient supplementation in medical school because they are studying the disease, not wellness”. To make things worse, pharmaceutical companies are only interested in patentable drugs and not natural therapies that provide little profit. Thus sadly, the average doctor today despite having taken the Hippocratic oath still rejects the Hippocrates dictum. 

Mainstream medicine’s common advice to us is often that nutrients have no inherent power to treat or prevent disease and that we don’t need to make a special effort to obtain these substances for our bodies. Our body is built using nutrients such as vitamins, minerals, amino acids and essential fatty acids. Would it not be but natural that these elements could heal the body as well? Complementary or nutritional medicine precisely takes this point into consideration. Nutritional medicine involves the use of a diet of healthy foods matched to patient’s biochemical individuality along with the proper and correct use of nutrient supplements to help maintain optimal physical and psychological health. While a shift to a healthier diet can improve health in itself, it is important to take nutritional supplementation. Our soil is routinely depleted of nutrients due to a variety of reasons. Modern agricultural practices such as using inorganic fertilizers, pesticides, over farming and acid rains cause the soil to be depleted of vital nutrients. Iodine deficient soils lead to goiter epidemic, zinc deficient soil lead to stunted growth and poor immune system, selenium deficient soil leads to premature aging. 

Dr. Robert Atkins a champion of complementary and nutritional therapy states several interesting case studies. One of Dr. Atkins patient, eleven year old Marie Speller was diagnosed with juvenile diabetes. Main stream doctors in such a case are traditionally taught that juvenile diabetes carries with it a life long sentence of requiring insulin. However Dr. Atkins treated Marie with calcium AEP along with other supplements and restored her to normal health within six months of therapy. Calcium AEP supplement given during the first year of illness of juvenile diabetes often reverses the disease completely wherein the patient no longer has to take insulin. To give another example, heart disease, the number one killer, arises in large part from atherosclerosis. Conventional medicine identifies cholesterol as a culprit and very often patient are put on cholesterol lowering drugs. These drugs do lower the cholesterol content but they also lower a vital nutrient called co-enzyme Q10. As a result many of these patients die sooner from causes other than heart disease if they take these medications than if they aren’t treated at all. However nothing is more effective in lowering cholesterol than pantethine, a derivative of the B-complex nutrient pantothenic acid. Pantethine has been shown in several case studies to lower triglycerides, LDL and total cholesterol while increasing the good cholesterol HDL. But one would seldom find any information about pantethine in a standard cardiovascular text books. 

In conclusion nutrients are enablers in that they give the body a chance to do what it needs to do by facilitating a natural physiological process, thus causing the body to function better. Usually the impact isn’t immediate as nutrients perform best over the long term. In contrast, drugs are helpful in controlling acute situations but become problematic when used long term as drugs are disablers or blocking agents. Drugs work by preventing a normal process from taking place, usually an enzyme performing a vital function. For drugs to work there must be a disease, only in this diseased condition can one hope to benefit from blocking an essential life function.

Thursday, February 6, 2014

The dark side of wheat


Wheat, the Bible tells us, is the “staff of life”. It has been the cornerstone of human diet since antiquity. For over ten thousand years, wheat has occupied a prominent place in caves, huts and on modern tables. However, almost all wheat consumed today bears little resemblance to what our ancestors ate over the millennia. There the rub.

At the onset of agriculture, the first farmers planted and harvested a form of wheat called “Einkorn” (triticum monococcum). Einkorn had a fairly simple genetic code containing fourteen chromosomes. A couple of millennia later, the  “Emmer” (triticum dicoccum) variety of wheat made its appearance. This was a genetic hybrid of Einkorn and a wild grass called “Goat Grass” (aegilops speltoides). Emmer was slightly more complex than Einkorn due to its twenty eight chromosome genetic structure, but still shared most of the genetic traits of its progenitor. Emmer and Einkorn would be the mainstays of man’s wheat-dominated diet for thousands of years.

During latter half of the 20th century, faced with the urgent problem of feeding the rapidly growing world population, scientists conducted intensive research into creating a new genetic wheat hybrid that would provide greater yield, and would be disease, drought, and heat resistant. Thus was born modern wheat: triticum aestivum. Today, modern wheat is the most consumed grain on earth and is responsible for  twenty percent of all human caloric consumption. While it is undoubtedly true that this form of wheat prevented mass starvation in the third world, it is also responsible for some of the most pernicious chronic degenerative diseases known to man.

Modern wheat contains forty two chromosomes, which puts it thousands of genes apart from the einkorn wheat of yore. Einkorn and modern wheat may look and taste the same, but there are major biochemical differences. Up to 75% of the total carbohydrate content in modern wheat consists of  Amylopectin-A, a compound composed of a chain of glucose units. This starch is efficiently digested, and causes a sharp rise in blood sugar levels immediately upon consumption. Its glycemic index (GI) - a measure of how quickly blood sugar levels rise after eating a type of food - is 72, higher than sucrose (table sugar: GI 59). High GI foods are directly implicated in hyperinsulinism, chronic inflammation due to excess deposition of visceral fat in the body, and the collection of autoimmune conditions commonly known as Syndrome X. In his bestselling book “Wheat Belly”, Dr. William Davis notes that while wheat and diabetes have travelled hand in hand throughout most of history, the arrival of modern wheat has precipitated an explosion in the rate of diabetes around the world today.

Other insidious effects of modern wheat are caused by the very component that gives it its unique cohesiveness and malleability: the protein Gluten. In about 1 in 100 people (98% of whom have the generic markers HLA-Q2 or DQ8), gluten triggers an immune response characterized by severe inflammation of the small intestine. This is manifested by incapacitating abdominal cramps, diarrhea, bloating and fatigue (see table 1), a collection of symptoms widely known as Celiac disease. If left untreated, this condition has been shown to severely damage intestinal walls. Celiac disease has been recognized and treated by the medical community for several decades. However, gluten is also responsible for another, less recognized condition known as non-Celiac gluten sensitivity, which has very Celiac-like symptoms (see table 1). This condition lacks the immune response, intestinal damage and genetic markers of celiac disease, but is linked to severe neurologic and psychiatric conditions including schizophrenia and cerebellar ataxia.

Gluten works its nefarious ways by stimulating the intestines to produce a protein called Zonulin. Zonulin damages the gut lining by breaking up the tight junctions between the intestinal cells thereby causing a leaky gut. As a result, partially digested food and intestinal microbes cross the gut barrier and enter the bloodstream. This exposure triggers an immune reaction, generating antibodies that attack the body’s own tissue leading to systemic inflammation. Various conditions such as heart disease, dementia, cancer and diabetes are linked to systemic inflammation.

Another alarming aspect of gluten is that when exposed to stomach acid and enzymes, it gets digested into shorter proteins or polypeptides called exorphins. These are like endorphins that one gets from an exercise high.  The exorphins can cross the blood brain barrier and bind to opioid receptors in the brain. These are the same receptors to which opiates such as heroin bind. Wheat exorphins behave exactly like a drug causing multiple problems with brain physiology including schizophrenia and autism. They also cause addictive behavior including cravings and binge eating. Thus gluten can alter mood and generate withdrawal symptoms upon its elimination.

Beyond gluten, there are about 20% non-gluten proteins can cause allergic or anaphylactic reactions in human (see table 1). Some of these non-gluten proteins include agglutinins, alpha amylases, thioredoxin and glycerinaldehyd-3-phosphare dehydrogenases. Exposure of these elements triggers asthma, rashes and wheat-dependent exercise-induced anaphylaxis (WDEIA) in susceptible individuals.

Strict elimination of gluten is the most effective way to reverse all the above conditions. A gluten-free lifestyle is also recommended for ostensibly healthy individuals because the majority of individuals who are sensitive to wheat may not exhibit any visible problems. Yet when they cut wheat out of their diets, they experience health benefits that include better mood, clearer skin, less fatigue, clearer thinking. Gluten elimination also helps those who struggle with autoimmune diseases, mental disorders, migraines, eczema and psoriasis, and joint pain. If you are suffering from any of the issues listed below it may be worthwhile to try a gluten free diet for a period of six weeks.
1) Genetic predisposition  or a family history of celiac disease or gluten intolerance
2) Presence of any digestive disease such as irritable bowel syndrome, colitis, poor intestinal permeability
3) Presence of food sensitivities that manifest as migraines, chronic fatigue, aches and pains, skin problems such as eczema, acne or pityriasis,
4) Presence or a family history of autoimmune conditions such as diabetes, rheumatoid arthritis and lupus.
5) Difficulty in losing weight.


Table 1: Some of the symptoms associated with celiac disease, wheat allergy and non celiac gluten sensitivity


Celiac Disease
Wheat Allergy
Non celiac gluten sensitivity
Gastrointestinal
Abdominal pain
Diarrhea
Constipation
Abdominal pain
Diarrhea
Vomiting

Abdominal pain
Diarrhea
Constipation
Nausea
Vomiting

Neurologic or
psychiatric
Headache
Brain fog
Fatigue
Numbness in hand and feet
Musculoskeletal pain
Ataxia

Dizziness
Headache
Headache
Brain fog
Fatigue
Numbness in hand and feet
Musculoskeletal pain
Other neurologic and psychiatric conditions
Other
Dermatitis herpetiformis
Weight loss
Eczema
Asthma
Rhinitis
Nausea
Itchiness
Rash
Nausea
Weight loss